Skincare that makes sense. See what's really in your products — in plain English.

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For informational purposes only — not medical advice. Always consult a dermatologist for skin concerns.

Synthetic Human Polypeptide-22

1% line markerAI-analyzed

INCI: SH-POLYPEPTIDE-22

skin conditioninganti-agingcell communicating ingredient

What it does

A synthetic human polypeptide that acts as a cell-communicating ingredient, often included in anti-aging and skin rejuvenating formulations to support cellular vitality and improve skin texture.

Skin Concerns

Beneficial for

agingfine lineswrinklessaggingtexturedullnesssun damageuneven tonedryness

Safety & Science

Safety summary

Generally considered safe for cosmetic use. Low potential for irritation or sensitization.

1% line marker

This ingredient is commonly used as a marker to identify where ingredients drop below 1% concentration on the label.

Found In Products

Related Ingredients

At a Glance

INCI Name: SH-POLYPEPTIDE-22
Common Name: Synthetic Human Polypeptide-22
Functions: skin conditioning, anti-aging, cell communicating ingredient
Products: 27 products

For informational purposes only. This is not medical advice. Always patch test new products and consult a dermatologist for skin concerns.

Synthetic Human Polypeptide-22 — Skincare Ingredient Guide — Dermasift — Dermasift